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Effects of NAC treatment on the level of free 15-F2t-isoprostane in plasma and heart tissue.
| C | D | D + NAC | |
|---|---|---|---|
| Plasma (pg/mL) |
125.1 ± 18.9 | 245.0 ± 19.1** | 150.7 ± 21.4# |
| Heart tissue (pg/mg protein) |
101.3 ± 17.3 | 208.5 ± 20.6* | 167.2 ± 18.5# |
All values are expressed as Mean ± S.E.M. n = 6 per group. Control (C) or STZ-induced diabetic rats with untreated (D) or treated with NAC (1.5 g/kg/day) for 4 weeks. *P < 0.05 versus C; # P < 0.05 versus D.
