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. Author manuscript; available in PMC: 2013 Jul 7.
Published in final edited form as: Semin Thromb Hemost. 2013 Mar 28;39(4):406–425. doi: 10.1055/s-0033-1338126

Table 4.

Contributors to hemorrhagic transformation

Factors Agent
Time from symptom onset rt-PA (duteplase)
Diastolic hypertension rt-PA
Low body mass rt-PA
Age rt-PA
Atrial fibrillation rt-PA
“Early” signs of ischemia rt-PA
rscu-PA
Plasminogen activator (e.g., rt-PA) rt-PA

Abbreviations: rscu-PA, recombinant single-chain urokinase plasminogen activator; rt-PA, recombinant tissue-type plasminogen activator.