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. Author manuscript; available in PMC: 2013 Jul 7.
Published in final edited form as: JAMA Ophthalmol. 2013 Jan;131(1):80–85. doi: 10.1001/jamaophthalmol.2013.986

Figure 2.

Figure 2

Signaling events regulated by stabilized HIF-1a contribute to the pathogenesis of ROP: Avascular retina and Vasoproliferation. (HIF1α, Hypoxia-inducible factor-1 ALPHA; VEGF, vascular endothelial growth factor; STAT3, signaling transducer and activator of transcription 3; EPO, erythropoietin; PRVD, physiologic retinal vascular development)