Skip to main content
. Author manuscript; available in PMC: 2014 May 29.
Published in final edited form as: J Am Chem Soc. 2013 May 16;135(21):7791–7794. doi: 10.1021/ja311636b

Figure 3. Identification of enzyme-cofactor pairs for MOF substrate labeling.

Figure 3

(a) Key residues surrounding the active site of MOF (PDB 2Y0M)11. (b) Heat map of engineered MOF activities to Ac-CoA analogs (see also Supplementary Fig. S4e). (c) MALDI-MS of H4-20 peptide modified by MOF-I317A/H273A-5HY-CoA pair.