Figure 4.

Dopamine levels in the nucleus accumbens following acute ethanol administration. Effect of anticatalase vector administration into the ventral tegmental area on dopamine release monitored in the ipsilateral nucleus accumbens. (A) Inhibition by anticatalase-lentiviral vector of dopamine efflux into the microdialysis fluid of nucleus accumbens (shell) induced by the systemic administration of ethanol (1 g/kg i.p.). (B) Anticatalase-lentiviral vector does not affect dopamine efflux into the microdialysis fluid of nucleus accumbens (shell) induced by d-amphetamine (0.1 mM) or (C) Anticatalase-lentiviral vector does not affect dopamine efflux into the microdialysis fluid of nucleus accumbens (shell) induced by KCl (100 mM) added to the microdialysis fluid. (From Karahanian et al., 2011).