Figure 6.

Ramipril restores nephrin and Snail expression in patients with type 2 diabetes to control levels. A: Representative images of immunofluorescence of nephrin (red) in glomeruli of diabetic patients, untreated or treated with ACE inhibitor. Control subjects were included for comparisons. B: Snail expression evaluated by immunofluorescence (green). C: Double immunofluorescence of nephrin and Snail. Insets, colocalization of nephrin with Snail (yellow, merged signal; twofold enlargement of boxed area).