Table 1. Effect of methanol and petroleum ether extracts of leaves of D. pulchellum on castor oil induced diarrhea in rats.
Groups | Treatment (p.o.) | Total number of feces | % Inhibition of defecation | Total number of diarrheal feces | % Inhibition of diarrhea |
I | Saline (2 mL/kg) | 18.18±1.92 | - | 11.05±1.08 | - |
II | Loperamide (5 mg/kg) | 7.76±0.66** | 57.32 | 5.00±0.33** | 54.75 |
III | DPM (200 mg/kg) | 12.12±0.97* | 33.30 | 7.52±0.37* | 31.95 |
IV | DPP (200 mg/kg) | 13.25±0.92 | 27.12 | 7.92±0.51 | 28.33 |
Values are expressed as mean±SEM (n=5). *P<0.05, **P<0.01 when compared with control group. DPM: D. pulchellum methanol extract; DPM: D. pulchellum petroleum ether extract.