Table 2. Effect of methanol and petroleum ether extracts of leaves of D. pulchellum on castor oil induced enteropooling in rats.
Groups | Treatment (p.o.) | Total length of intestinal content (g) | Volume of intestinal content (mL) | Inhibition (%) |
I | Saline (2 mL/kg) | 3.18±0.07 | 2.79±0.18 | - |
II | Loperamide (5 mg/kg) | 1.61±0.04** | 1.18±0.10** | 57.71 |
III | DPM (200 mg/kg) | 2.27±0.91* | 1.99±0.64* | 28.67 |
IV | DPP (200 mg/kg) | 2.48±0.20* | 2.08±0.10* | 25.45 |
Values are expressed as mean±SEM (n=5). *P<0.05, **P<0.01 when compared with control group. DPM: D. pulchellum methanol extract DPM: D. pulchellum petroleum ether extract.