Table 1.
Thickness |
Surface area |
Volume |
|||||||
---|---|---|---|---|---|---|---|---|---|
Younger | Older | Mild AD | Younger | Older | Mild AD | Younger | Older | Mild AD | |
ERC | |||||||||
LH | 2.88 (0.26) | 2.75 (0.32) | 2.35 (0.39)** | 187 (48) | 173 (56)* | 152 (44) | 892 (190) | 773 (254)* | 553 (194)** |
RH | 2.66 (0.39) | 2.54 (0.32) | 2.11 (0.36)** | 199 (46) | 167 (52)* | 154 (54) | 847 (195) | 676 (223)* | 495 (218)** |
PRC | |||||||||
LH | 2.12 (0.46) | 2.15 (0.45) | 1.87 (0.41)** | 248 (81) | 219 (72) | 249 (90) | 601 (197) | 532 (185) | 521 (212) |
RH | 2.09 (0.42) | 2.08 (0.35) | 1.85 (0.36)** | 219 (70) | 220 (66) | 210 (85) | 519 (135) | 525 (163) | 459 (170) |
PPHC | |||||||||
LH | 1.96 (0.21) | 1.94 (0.26) | 1.83 (0.29)** | 539 (68) | 478 (81)* | 481 (81) | 1263 (226) | 1075 (242)* | 989 (231) |
RH | 1.86 (0.20) | 1.92 (0.21) | 1.77 (0.26)** | 502 (59) | 445 (84)* | 461 (100) | 1078 (173) | 970 (200)* | 916 (271) |
Values represent mean (standard deviation). ERC: entorhinal cortex; PRC: perirhinal cortex; PPHC: posterior parahippocampal cortex; AD: Alzheimer's disease; LH: left hemisphere; RH: right hemisphere.
Normal Older group is different from Normal Younger group, p < 0.05.
Mild AD group is different from Normal Older group, p < 0.05.