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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Pharm Res. 2013 Mar 8;30(6):1608–1627. doi: 10.1007/s11095-013-1001-z

Table 4.

Key turbulence-based factors expected to influence deagglomeration.

Inhaler number and flow ratea kb (m2/s2) TIb (%) ωb (1/s) NDSDb (dimensionless) MMDc (μm)
1 at 45 LPM 4.2 13.5 61,949 82.6 1.35 (0.02)d
2 at 45 LPM 5.6 20.1 111,303 148.4 1.21 (0.1)
3 at 45 LPM 12.1 47.2 64,846 86.5 1.36 (0.07)
4 at 60 LPM 143.0 35.3 96,020 96.0 1.27 (0.07)
4 at 75 LPM 474.2 50.5 132,866 106.3 1.27 (0.14)
5 at 45 LPM 9.5 38.3 72,673 96.9 1.31 (0.03)
6 at 45 LPM 19.1 26.03 127,277 169.7 0.98 (0.04)
6 at 60 LPM 28.3 23.9 148,323 148.3 1.03 (0.05)
7 at 45 LPM 10.0 30.7 75,565 100.8 1.28 (0.03)
8 at 45 LPM 6.7 22.2 115,799 154.4 1.18 (0.06)
a

Denotes inhaler number and flow rate (LPM)

b

Volume-averaged quantities within the flow passage of each inhaler

c

Estimated based on measured MMAD and the skeletal density of the primary particles (ρp = 1.325 g/cm3)

d

Standard deviations (SD) of experimental results based on n ≥ 3 trials