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. Author manuscript; available in PMC: 2013 Jul 8.
Published in final edited form as: Nat Neurosci. 2012 Jun;15(6):813–815. doi: 10.1038/nn.3099

Figure 3. CB knockdown in VTA DA neurons enhanced Pv and synaptic depression during AP bursts.

Figure 3

(a) Single AP responses are significantly higher and lower in CB KD and overexpression compared to control, 3-way ANOVA: p < 0.0001. Inset, representative 1 AP responses for each condition, scale: 0.5% TP, 50 ms. (b, c) Pv (b) and RRP (c) measured from control, CB KD and CB KD with rescue neurons plotted against relative expression of CB. (d) Amount of exocytosis relative to the 1st AP response plotted against AP number (straight line shows zero depression) in CB KD DA and control DA neurons.