(a) Single AP responses are significantly higher and lower in CB KD and overexpression compared to control, 3-way ANOVA: p < 0.0001. Inset, representative 1 AP responses for each condition, scale: 0.5% TP, 50 ms. (b, c) Pv (b) and RRP (c) measured from control, CB KD and CB KD with rescue neurons plotted against relative expression of CB. (d) Amount of exocytosis relative to the 1st AP response plotted against AP number (straight line shows zero depression) in CB KD DA and control DA neurons.