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Effect of the histone deacetylase inhibitors sodium butyrate (NaB), sirtinol, trichostatin A (TSA) and suberoylanilide hydroxamic acid (SAHA) on TGF-β1-induced PAI-1 expression (A). Data plotted is a summary of western blot analyses. Preincubation with NaB concentrations of 5–10 mM completely ablates TGF–β1-stimulated PAI-1 expression (B).
