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AS-IV reduced the protein content of MCP-1, ICAM-1, and TNF-α in rats with ischemic AKI. The protein content of TNF-α (a), MCP-1 (b), and ICAM-1 (c) in renal tissues from sham, vehicle-, or AS-IV-pretreated rats at 12 h of reperfusion. The protein content of TNF-α (d), MCP-1 (e), and ICAM-1 (f) in renal tissues from sham, vehicle-, or AS-IV-pretreated rats at 24 h of reperfusion. Results are expressed as mean ± SD (n = 8). *P < 0.05 versus Sham group; # P < 0.05 versus Veh group.
