Fig. 5.

PMN genes involved in apoptosis and cell survival are altered during infection with F. tularensis LVS. Differentially expressed genes (all p < 0.05) linked to apoptosis or cell survival in previous studies are shown along with the mean fold change in expression at each time point as indicated by the color-coded scale bar. In some cases, gene names are followed by the common name for the encoded protein as a reference. Upregulated transcripts linked to antiapoptosis or cell survival are marked with an asterisk. Downregulated transcripts associated with proapoptotic or prodeath functions are marked with a black ×.