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. 2013 Jun 19;2013:370526. doi: 10.1155/2013/370526

Figure 2.

Figure 2

MPTP-induced neurotoxicity is attenuated in the striatum of MMP-3−/− mouse brain. Striatal tissues obtained from the same animals as used in Figure 1 were immunostained with TH antibody for DA fibers. Animals were treated with PBS as a control (a and c) and MPTP (b and d). (e) Bars represent optical density of TH-ip fibers in the striatum. Scale bar, 250 μm. Five to six animals were used for each experimental group. Two-way ANOVA with Bonferroni post hoc test (F(1,15) = 22.22, P < 0.001),  ***P < 0.001, significantly different from PBS-injected MMP-3+/+ mice; # P < 0.05, significantly different from MPTP-injected MMP-3+/+ mice.