Fig. 3.
Evidence for involvement of Asn1573.51 in binding of BZT and JHW007. (A, B, C) Inhibition of [3H]dopamine uptake by CFT (A), BZT (B) or JHW007 (C). The uptake experiments were performed using indicated concentrations of inhibitor on COS7 cells transiently expressing wild type (WT) DAT (black circles) or N157A (blue squares). Data are means ± S.E. of 3 to 17 experiments performed in triplicate.