Skip to main content
. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Epilepsia. 2013 Apr 5;54(7):1223–1231. doi: 10.1111/epi.12150

Figure 3. 4-AP inhibition of IA in DGCs is slowed but intact after seizure-inducing hypoxia.

Figure 3

(A) Representative raw traces using the IA activation protocol with test step to +30 mV are shown before and after 5-minute application of 10 mM 4-AP. (B, C) Summary data illustrate greater apparent inhibition of IA by 4-AP after 5-minute application in the control group compared to the hypoxia-treated group. However, prolonged 4-AP application (>15 minutes) resulted in complete inhibition of IA in both groups (see Results).