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IVIG induced hyperphosphorylation of ERK1/2 and downregulated p38 MAPK phosphorylation in BMDC stimulated with LPS. Cells were stimulated with LPS (500 ng/mL) in the presence or absence of IVIG (10 mg/mL) for 15 min. Cell lysates were incubated with specific antibodies against NFκ-B, ERK1/2, p38 MAPK, and JNK and their phosphorylated forms and were analyzed by respective immunoblottings.
