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. Author manuscript; available in PMC: 2013 Sep 25.
Published in final edited form as: ACS Nano. 2012 Aug 1;6(9):7928–7934. doi: 10.1021/nn3023624

Figure 1.

Figure 1

Schematic representation of the experimental methodology to generate stretched and oriented chromatin arrays on a solid support. (1), and (2) represent the assembly and stretching process by capillarity. (1) The microstructured PDMS stamp is placed on a translation stage controlled in speed. A droplet of extracted chromatin in solution is deposited on the stamp. (2) The liquid meniscus of the solution containing the extracted chromatin is dragged over the microstructured PDMS stamp at controlled speed. The evaporation phenomenon is represented in red. The molecules are physically trapped and stretched as the meniscus is displaced across the substrate. (3) represents the transfer-printing of the obtained chromatin array on an APTES-coated cover slip by contacting the PDMS stamp with the APTES-coated surface for two minutes and then peeling it away.