Table 3.
Dose level (μg/kg) | Cancer diagnosis | Cycles | DLT | Response |
---|---|---|---|---|
100 | Urachal | 2 | No | PD |
100 | Prostate | 6 | No | SD |
100 | Sarcoma | 2 | No | PD |
200 | Sarcoma | 5 | No | SD |
200 | Pancreatic | 2 | No | PD |
200 | Colorectal | 2 | No | PD |
400 | Colorectal | 2 | No | PD |
400 | Pancreatic | 1 | Yes | n/a |
400 | Prostate | 2 | No | PD |
400 | Colorectal | 6 | No | SD |
400 | Colorectal | 1 | No | PD |
400 | Colorectal | 2 | No | PD |
700 | Colorectal | 2 | No | PD |
700 | Lung | 3 | Yes | n/a |
700 | Anal | 2 | No | PD |
700 | Sarcoma | 14 | No | MR |
700 | Prostate | 1 | Yes | n/a |
700 | Head and neck | 1 | No | PD |
Abbreviations: PD, progressive disease; SD, stable disease; MR, minor response; n/a, not available.