Table 2.

Treatment and outcome of patients with anti-NMDA receptor encephalitis

	Patient 1	Patient 2	Patient 3
Initial therapy
IVIG	Yes	Yes	Yes
IV methyl-	Yes	Yes	No
prednisolone pulse
Oral prednisone	Yes	No	No
IV Rituximab	Yes	No	No
Duration of therapy	7 months	7 months	3 months
Course
Relapse	No	yes	yes
Time to relapse	-	13 months	3 months
Re-treatment	-	IVIG×6 months	Rituximab
			plus IVIG×6 months
Outcomes
Time at last follow-up	12 months	14 months	4 months
Neurological deficits	None	Seizures	Seizures
at last follow-up		Speech difficulties
		Memory impairment

IV = intravenous, IVIG = intravenous immunoglobulin