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Histograms of minor allele frequencies (MAF) of SNPs from chromosomes 21 and 22 in reference panels from YRI and CEU populations in HapMap II (HMII) and 1000 Genomes (1KG) Projects. Histogram of MAF of SNPs in HyperGEN African Americans genotyped on Affymetrix SNP Array 6.0 is also shown for comparison. Rare and low frequency variants are in the red bin. Histograms of MAF across the genome were similar.
