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. Author manuscript; available in PMC: 2013 Jul 8.
Published in final edited form as: J Investig Dermatol Symp Proc. 2011 Dec;15(1):53–62. doi: 10.1038/jidsymp.2011.6

Figure 1. Association of different vascular and immune structures with sensory nerves in human facial skin of rosacea patients, as shown by double immunofluorescence staining.

Figure 1

Colocalization of sensory nerves (PGP9.5) was determined in combination with CD31 for blood vessels (a), podoplanin (Pod) for lymphatic vessels (b), tryptase (Try) for mast cells (c), and smooth muscle actin (SMA) for myofibroblasts or blood vessels (d). Our data show a close anatomical association of unmyelinated nerves, especially with blood vessels and mast cells, and less with lymphatic vessels or myofibroblasts (bar = 300 μm; a–c and bar = 100 μm; d).