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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: J Mol Cell Cardiol. 2012 Jul 28;53(4):552–558. doi: 10.1016/j.yjmcc.2012.07.009

Fig. 3.

Fig. 3

Localization of RNA POLII and its features as revealed by STED. Panel A, NRVMs were labeled with histone H3 and RNA POLII, simultaneously visualized via STED (red) or conventional confocal (cyan), respectively. Panel B, same as previous panel with the RNA POLII visualized in STED channel (red) and histone H3 in conventional confocal (cyan). RNA POLII displayed diffuse staining throughout the nucleus, with concentrations in the nuclear periphery. This pattern was unique to NRVMs, as neurons displayed a more homogenous distribution of RNA POLII despite a similar global histone H3 pattern (panel C). Bar is 1 μm in all images.