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. 2013 Apr 18;2(2):e24558. doi: 10.4161/worm.24558

graphic file with name worm-2-e24558-g6.jpg

Figure 6. Plate-level phenotypes of mutants and toxin-treated animals. (A) The results are plotted similar to Figure 2. The him-8, osm-5 and dat-1 animals are comparable to the N2 control but lin-11 animals show reduced speed (**: p < 0.01). (B) Exposure to 6-OHDA, MPTP and rotenone causes weak Unc phenotype. Except for 6-OHDA 4 h cases that caused roughly 40% of animals to become Unc, all other treatments affected less than 3% of animals. The numbers of animals examined for each condition are as follows: 6-OHDA - 605 for 1 h and 420 for 4 h, and N2 control - 220; MPTP - 502 and control - 192; Rotenone - 353 and control - 163. (C) The chemotaxis responses of N2 and 6-OHDA 1 h-exposed animals toward NaCl chemoattractant. The toxin-treated worms show normal behavior.