Table 2. p53 Response elements in the PRODH2 gene.

	Name	Location (bp from TSS)	Mismatches HS 1	Mismatches HS 2	Spacer (bp)	Sequence
1	-1.3	Promoter, -1,281	2	2	3	cAGCATGTTg GGA GGACAAGTag
2	-0.5	Promoter, -0,534	2	3	3	ActCTAGCCT GGG cAACAAGagT
3	-0.27	Promoter, -0,267	1	2	6	GtACATGTTT CCTGCT GtcCATGTTT
4	+10.5	Intron 9,+10,519	2	NA	NA	cAGCAAGaCC
	5	+10.7	Intron 9,+10,685	NA	NA	AAGCAAGTCC

HS: half-site

Bold: REs selected for experimental validation

Bold/underlined: bases that are part of the indicated RE; italic: spacers; minuscule: mismatches within RE