Figure 1. The two components of the magnetic bead-based extraction method.

A) DNA is adsorbed to silica-coated magnetic beads previously lyophilized with DNA-silica adsorption buffer in the bulb of a transfer pipette. After mixing, the beads are transferred directly into the small diameter tubing by depressing the bulb. B) The small diameter tubing “extraction cassette” is shown with processing solutions separated by air gaps. DNA adsorbed to silica-coated magnetic beads is pulled through each processing solution by an external magnet and eluted in the final water chamber.