Skip to main content
. 2013 Jun 7;21(1):47. doi: 10.1186/2008-2231-21-47

Table 2.

Results (IC50, μM) of in vitro acetylcholinesterase assay of compounds 4a-4l

Compound 4a 4b 4c 4d 4e 4f 4g 4h 4i 4j 4k 4l Donepezil
R
2-Cl
3-Cl
4-Cl
2-F
3-F
4-F
3-OCH3
4-OCH3
2-NO2
3-NO2
4-NO2
H
-
IC50(μM) 0.91 ± 0.045 85 ± 12 26 ± 5 23 ± 7 74 ± 11 42 ± 8 5.5 ± 0.7 72 ± 9 36 ± 5 59 ± 6 40 ± 4 9 ± 2 0.14 ± 0.03