Table 5.
Comparison of Mean FsIQ, VIQ, PIQ in different populations with sickle cell disease in Europe and USA
| Age years | % with FsIQ<75 | FSIQ | VIQ | PIQ | % Immigrant | % mother-tongue language of hosting country | |
|---|---|---|---|---|---|---|---|
| USA |
8.5 |
NR |
70.8-82.8-90* |
72.1-79.9-88.8* |
74.1-88.1-92.9* |
NR |
NR but IQ lower in children speaking two languages at home |
| Armstrong 1996 | |||||||
| USA |
13.5 |
9 |
77.3-81.1-86.7* |
79.9-77.1-85.3* |
77.3-81.1-86.7* |
NR |
NR |
| Wang 2001 | |||||||
| USA |
9.5 |
NR |
78.6-81.1** |
74.1-84.6** |
77.5-78.9** |
NR |
NR |
| Steen 2003 | |||||||
| USA |
9.75 |
NR |
75.05-81.91-81.67* |
79.59-88.73-85.60* |
74.73-77.73-80.80* |
NR |
NR |
| Brown 2000 | |||||||
| USA |
8.2 |
NR |
72.7-85-90.2* |
74.2-84.6-93* |
75.5-83.3-89* |
NR |
NR |
| Thompson 2003 | |||||||
| USA |
10 |
NR |
87.15-90.33-91.22§ |
89.56-94.86-92§ |
86.9-87.93-91.96§ |
NR |
100 |
| Kral MC 2003 | |||||||
| UK |
8.73-11.58 |
NR |
67.6-79-86.03* |
73.6-85.25-89.07* |
67.80-79.75-85.57* |
NR |
NR |
| Watkins 1998 | |||||||
| France |
5-15 |
30.7 |
83.9-82.6-86.6** |
90.4-85.8-93.3** |
80.6-83.5-82.3 |
NR |
NR but performed in children living in France > 2 yrs |
| Bernaudin 2000 | |||||||
| UK |
infants |
NR |
82.5-87.4** |
BIN study early language development in infants |
BIN measures of early language development in infants |
100 |
BIN measures of All families spoke English, and in the majority of cases, infants were also exposed to a non-English |
| Hogan 2006 | |||||||
| The Netherlands |
|
|
79-80** |
80-82** |
80-77** |
NR |
NR |
| Hijmans 2010 | |||||||
| The Netherlands |
12.2 |
30 |
80 |
83 |
79 |
100 |
46 (immigrants from Netherland Antilles) |
| Hijmans 2011 | |||||||
| This paper | 8.9 | 25 | 86.9 | 84.5 | 91.7 | 100 | 1 |
*Clinical stroke Silent infarct on MRI- Normal MRI; **Silent Infarct on MRI Normal MRI; § Abnormal TCD-Conditional TCD-Normal TCD, NR not reported.