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. 2013 Mar 27;13:160. doi: 10.1186/1471-2407-13-160

Table 1.

Previous published genome wide association studies considered in the present study

A) Published studies of association with Melanoma
Study
Gene
SNP
Allele
OR
p-value
MM association
MacGregor et al. 2011
PARP1
rs3219090
A
0.82
9.5 × 10-7
Protective
Barrett et al. 2011
ATM
rs1801516
A
0.79
4.80 × 10-7
Protective
CASP8
rs13016963
A
1.18
5.68 × 10-7
Risk
MX2
rs45430
G
0.85
5.60 × 10-7
Protective
CCND1
rs1485993
A
1.19
4.15 × 10-7
Risk
Duffy et al. 2010
IRF4
rs12203592
C
1.15
4 × 10-3
Protective
B) Previous studies of association with Vitamin D levels
 
Published Data
[VitD] < 75 nmol/L levels
[VitD] < 50 nmol/L levels
Study
Gene
SNP
Allele
OR (CI 95%)
p-value
OR (CI 95%)
p-value
Wang et al. 2011
CYP2R1
rs10741657
A
1.21 (1.45-1.29)
9.4 × 10-11
1.06 (1.00-1.13)
0.06
 
NADSYN1
rs7944926
A
1.21 (1.14-1.29)
4.1 × 10-10
1.21 (1.14-1.29)
4.7 × 10-9
  NADSYN1 rs12785878 G - - - -

[VitD] means concentration of vitamin D on plasma.

OR: Odds Ratio.

The allele referes to the one considered as risk allele in the appropriated studies.