Table 2.
Allelic frequencies in Spanish cases and controls
| Gene | SNP | Minor allele | p-HWE | MAF Controls | MAF Cases | p-value | trend* |
|---|---|---|---|---|---|---|---|
|
PARPI |
rs3219090 |
A |
0.27 |
0.329 |
0.275 |
0.023 |
0.028 |
|
CASP8 |
rs13016963 |
A |
0.98 |
0.414 |
0.399 |
0.542 |
0.561 |
|
MX2 |
rs45430 |
G |
0.93 |
0.380 |
0.392 |
0.624 |
0.603 |
|
CYP2R1 |
rs10741657 |
A |
0.16 |
0.378 |
0.381 |
0.891 |
0.867 |
|
CCND1 |
rs1485993 |
T |
0.48 |
0.448 |
0.438 |
0.697 |
0.652 |
|
NADSYN1 |
rs7944926 |
A |
0.27 |
0.355 |
0.333 |
0.363 |
0.392 |
|
NADSYN1 |
rs12785878 |
G |
0.75 |
0.369 |
0.330 |
0.102 |
0.109 |
|
ATM |
rs1801516 |
A |
0.04 |
0.145 |
0.121 |
0.185 |
0.208 |
| IRF4 | rs12203592 | T | 0.01 | 0.152 | 0.148 | 0.8 | 0.720 |
p-HWE: p-value obtained for deviation from Hardy-Weinberg Equilibrium. MAF: Minor Allele Frequency. Bold indicates statistically significant results.
*Trend p-values are obtained by performing a Cochran-Armitage test for trend.