Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Potential influence of Klotho on adipocyte development. Adipocytes develop from MSCs through two stages of maturation. WNT and δFosB are involved in the differentiation of MSCs to adipoblasts, whereas PPAR-γ drives differentiation of preadipocytes to adipocytes. Klotho could potentially influence both the adipogenic lineage commitment of MSCs and adipocytic maturation, but these roles remain to be confirmed experimentally. Abbreviation: MSC, mesenchymal stem cell.
