Table 3.
Effect of the low WEC A allele in sheep depending on the mechanism by which sheep reduce WEC
| Mechanism of the A allele | Sheep genotype |
Mean adult wormsa |
WEC meanb |
Effect of allele A (α%) |
Mean pasture L3c |
|||||
|---|---|---|---|---|---|---|---|---|---|---|
| Count | p | Age (days) | Count (epg) | p | Max nb (x107) | p | Age (days) | |||
|
E |
aa |
11 769 |
0.500 |
31.3 |
487 |
0.500 |
|
|
|
|
| |
Aa |
8 776 |
0.516 |
31.2 |
352 |
0.516 |
22.4 |
4.72 |
0.489 |
15.2 |
| |
AA |
6 610 |
0.531 |
31.2 |
268 |
0.531 |
|
|
|
|
|
M |
aa |
12 581 |
0.500 |
30.7 |
501 |
0.500 |
|
|
|
|
| |
Aa |
8 916 |
0.518 |
27.3 |
356 |
0.518 |
29.7 |
4.93 |
0.488 |
15.2 |
| |
AA |
5 067 |
0.534 |
25.6 |
203 |
0.534 |
|
|
|
|
|
F |
aa |
11 134 |
0.500 |
31.3 |
449 |
0.500 |
|
|
|
|
| |
Aa |
11 344 |
0.500 |
31.3 |
354 |
0.508 |
21.9 |
4.22 |
0.488 |
15.2 |
| AA | 11 267 | 0.500 | 31.3 | 252 | 0.516 | |||||
Postulated mechanisms to reduce WEC in sheep through the ‘resistance’ A allele: E = reduced worm establishment, M = increased worm mortality and F = reduced female worm fecundity; epg = eggs per gram; anumber, age, and frequency of the alternate B allele (p) for adult worms; baverage effect on WEC (α) and p for deposited eggs; cnumber, frequency of p and age for infective L3 larvae on pasture.