Table 1.
Baseline characteristics and intra-operative data of enrolled patients randomized to placebo or rHuEPO group
| Placebo group (n = 50) | rHuEPO group (n = 50) | p value | |
|---|---|---|---|
| Age (years) |
60 ± 16 |
63 ± 16 |
0.39 |
| Sex: Male (%) |
52 |
62 |
0.31 |
| Underlining Disease: |
|
|
|
| Diabetes mellitus (%) |
34 |
27 |
0.54 |
| Hypertension (%) |
63 |
79 |
0.15 |
| Dyslipidemia (%) |
38 |
36 |
0.92 |
|
Preoperative medication: |
|
||
| ACE inhibitor (%) |
44 |
46 |
0.72 |
| Angiotensin II recertor blocker (%) |
22 |
24 |
0.86 |
| Beta blocker (%) |
46 |
50 |
0.62 |
| Calcium channel blocker (%) |
34 |
36 |
0.68 |
| Diuretic (%) |
26 |
30 |
0.24 |
| Platelet inhibitor (%) |
74 |
82 |
0.16 |
| Statin (%) |
62 |
60 |
0.84 |
| Serum creatinine (SCr), mg/dL |
1.05 ± 0.45 |
1.05 ± 0.27 |
0.94 |
| eGFR (mL/min/1.73 m2) |
67 ± 33 |
64 ± 29 |
0.44 |
| eGFR > 60 (%) |
48 |
38 |
0.48 |
| eGFR < 60 (%) |
52 |
62 |
0.32 |
| Hemoglobin (g/dL) |
12.2 ± 1.9 |
12.3 ± 1.7 |
0.72 |
| Hematocrit (%) |
36.2 ± 6.6 |
37.1 ± 5.2 |
0.45 |
| Reticulocyte count (%) |
1.19 ± 0.66 |
1.11 ± 0.63 |
0.53 |
|
Intra-operative data: |
|
||
| Operation time (minutes) |
353 ± 76 |
341 ± 88 |
0.44 |
| Arterial clamp time (minutes) |
87 ± 31 |
82 ± 38 |
0.52 |
| Central venous pressure (cm H2O) |
4.81 ± 4.07 |
4.52 ± 3.93 |
0.72 |
| Intraoperative intake (mL) |
1,628 ± 660 |
1,530 ± 477 |
0.55 |
| Intraoperative output (mL) |
958 ± 673 |
1172 ± 973 |
0.34 |
| Intraoperative urine output (mL/kg/hour) | 2.89 ± 1.73 | 2.96 ± 2.46 | 0.89 |
eGFR indicates estimated glomerular filtration rate.