Table 1.
Summary of patients’ demographic and clinical characteristics
|
Characteristics of study population |
Experienced cohort 1 |
Newly treated cohort 2 |
||||
|---|---|---|---|---|---|---|
|
(n = 1894) |
Intervention |
Control |
p-value |
Intervention |
Control |
p-value |
| (n = 446) | (n = 352) | (n = 520) | (n = 576) | |||
| Female (n = 1258) |
289 (64.8%) |
248 (70.5%) |
0.0908 |
337 (64.8%) |
384 (66.7%) |
0.5171 |
| Mean age (95% CI) |
39.4 (38.3–40.5) |
38 (37.1–38.9) |
0.065 |
38.6 (37.7–39.5) |
39.2 (38.4–40.1) |
0.349 |
|
Marital status (%) | ||||||
| Single |
72 (16.1%) |
43 (12.2%) |
0.1157 |
79 (15.2%) |
79 (13.7%) |
0.1987 |
| Divorced/Widowed |
119 (26.7%) |
114 (32.4%) |
140 (26.9%) |
186 (32.3%) |
||
| Married |
181 (40.6%) |
159 (45.2%) |
253 (48.7%) |
268 (46.5%) |
||
|
Weight at start of follow-up—mean (95% CI) | ||||||
| Male |
58.5 (56.7,60.3) |
58.3 (56.8,59.9) |
0.8974 |
54.9 (53.5,56.3) |
57.3 (56,58.5) |
0.0144 |
| Female |
54.8 (53.5,56.0) |
55 (53.9,56.1) |
0.796 |
52.3 (51.1,53.5) |
52.8 (51.7,53.8) |
0.5529 |
|
WHO stage at ART initiation (%) | ||||||
| Stage 1 |
14 (3.1%) |
46 (13.1%) |
<0.0001 |
50 (9.6%) |
88 (15.3%) |
0.0003 |
| Stage 2 |
61 (13.7%) |
84 (23.9%) |
146 (28.1%) |
199 (34.5%) |
||
| Stage 3 |
278 (62.3%) |
172 (48.9%) |
247 (47.5%) |
224 (38.9%) |
||
| Stage 4 |
31 (7%) |
22 (6.3%) |
31 (6%) |
21 (3.6%) |
||
|
CD4 value at ART initiation—mean (95% CI) | ||||||
| CD4 value |
293 (269.1,316.9) |
334.3 (309.8,358.8) |
0.0183 |
169.2 (154.5,183.9) |
189.4 (176.1,202.7) |
0.0466 |
|
Evidence of adherence counselling prior to ART initiation | ||||||
| Adherence counselling | 387 (86.8%) | 238 (67.6%) | <0.0001 | 457 (87.9%) | 401 (69.6%) | < 0.0001 |
*Missing data: marital status n = 201; WHO staging n = 180; initial CD4 n = 470; initial adherence counseling n = 3.
NB: Figures in bold show significant differences.