Table 3.
The immune response to vaccine B (B/Malaysia/2506/2004-like virus)/(A/Wisconsin/67/2005(H3N2)-like virus)/A (A/New Caledonia/20/99 (H1N1)-like virus) by hemagglutination inhibition (HAI) test between 55 caregivers and 61 controls
| Caregiver (n = 55) | Control (n = 61) | Total (n = 116) | |||
|---|---|---|---|---|---|
| p value = 0.758 | p value = 0.776 | p value = 0.205 | |||
| Influenza B (B/Malaysia/2506/2004-like virus)c | |||||
| Pre-vaccine immunitya | 34 (62 %) | 36 (59 %) | 70 (60 %) | ||
| No pre-vaccine immunityb | 21 (38 %) | 25 (41 %) | 46 (40 %) | ||
| Influenza A (A/Wisconsin/67/2005(H3N2)-like virus)c | |||||
| Pre-vaccine immunitya | 43 (78 %) | 49 (80 %) | 92 (79 %) | ||
| No pre-vaccine immunityb | 12 (22 %) | 12 (20 %) | 24 (21 %) | ||
| Influenza A (A/New Caledonia/20/99 (H1N1)-like virus)c | |||||
| Pre-vaccine immunitya | 44 (80 %) | 54 (89 %) | 98 (85 %) | ||
| No pre-vaccine immunityb | 11 (20 %) | 7 (12 %) | 18 (16 %) | ||
Differences in the percentage between the two groups were compared by chi-square test
aPre-vaccine immunity was defined as pre-vaccine HAI titer of ≥1:10
bNo pre-vaccine immunity was defined as pre-vaccine HAI titer of <1:10
cResponder was defined as subject with no pre-vaccine immunity having HAI titer of ≥1:40 or subject with pre-vaccine immunity having HAI titer of ≥4-fold at week 6 No-responder was defined as subject with no pre-vaccine immunity having HAI titer of <1:40 or subject with pre-vaccine immunity having HAI titer of <4-fold at week 6