Table 4.
The immune responder at week 6 to vaccine B (B/Malaysia/2506/2004-like virus)/(A/Wisconsin/67/2005(H3N2)-like virus)/A (A/New Caledonia/20/99 (H1N1)-like virus) by hemagglutination inhibition (HAI) test between 55 caregivers and 61 controls
| Caregiver (n = 55) | Control (n = 61) | Total (n = 116) | |||
|---|---|---|---|---|---|
| p valued = 0.936 | p valued = 0.296 | p valued = 0.490 | |||
| Responderc to influenza B (B/Malaysia/2506/2004-like virus) | |||||
| pre-vaccine immunitya | 11 (20 %) | 9 (15 %) | 20 (17 %) | ||
| No pre-vaccine immunityb | 4 (7 %) | 8 (13 %) | 12 (10 %) | ||
| 15 (27 %) | 17 (28 %) | 32 (28 %) | |||
| Responderc to influenza A (A/Wisconsin/67/2005(H3N2)-like virus) | |||||
| pre-vaccine immunitya | 12 (22 %) | 15 (25 %) | 27 (23 %) | ||
| No pre-vaccine immunityb | 4 (7 %) | 8 (13 %) | 12 (10 %) | ||
| 16 (29 %) | 23 (38 %) | 39 (34 %) | |||
| Responderc to Influenza A (A/New Caledonia/20/99 (H1N1)-like virus) | |||||
| pre-vaccine immunitya | 9 (16 %) | 14 (23 %) | 23 (20 %) | ||
| No pre-vaccine immunityb | 4 (7 %) | 3 (5 %) | 7 (6 %) | ||
| 13 (24 %) | 17 (28 %) | 30 (26 %) | |||
aPre-vaccine immunity was defined as pre-vaccine HAI titer of ≥1:10
bNo pre-vaccine immunity was defined as pre-vaccine HAI titer of <1:10
cResponder was defined - subject with no pre-vaccine immunity having HAI titer of ≥1:40 or subject with pre-vaccine immunity having HAI titer of ≥4-fold at week 6 No-responder was defined as subject with no pre-vaccine immunity having HAI titer of <1:40 or subject with pre-vaccine immunity having HAI titer of <4-fold at week 6
dLogistic regression of immune response to influenza vaccine is associated with caregiver/control group