Table 7.
Summary of multilevel modeling results of lymphocytes subsets in both groups over time
| Coefficient | SE | p valuea | |
|---|---|---|---|
| % of total T lymphocytes (ln) | |||
| Case (reference, control) | −0.013 | 0.032 | 0.6845 |
| Time | |||
| Linear | −0.004 | 0.005 | 0.4237 |
| Interaction Effect | |||
| Case × time linear | −0.002 | 0.006 | 0.7389 |
| No. of total T Lymphocytes (ln) | |||
| Case (reference, control) | −0.140 | −0.05 | 0.0051 |
| Time | |||
| Linear | −0.05 | 0.015 | 0.0009 |
| Quadratic | −0.074 | 0.026 | 0.0044 |
| Interaction effect | |||
| Case × time linear | 0.020 | 0.046 | 0.6637 |
| Case × time quadratic | 0.018 | 0.036 | 0.6171 |
| % of T suppressor lymphocytes (ln) | |||
| Case (reference, control) | −0.013 | 0.032 | 0.6845 |
| Time | |||
| Linear | −0.004 | 0.005 | 0.4237 |
| Interaction effect | |||
| Case × time linear | −0.002 | 0.006 | 0.7389 |
| No. of T suppressor lymphocytes (ln) | |||
| Case (reference, control) | −0.044 | 0.086 | 0.6089 |
| Time | |||
| Linear | −0.037 | 0.017 | 0.0295 |
| Quadratic | −0.060 | 0.028 | 0.0321 |
| Interaction effect | |||
| Case × time linear | −0.034 | 0.024 | 0.1566 |
| Case × time quadratic | −0.014 | 0.040 | 0.7263 |
| % of T helper lymphocytes (ln) | |||
| Case (reference, control) | −0.090 | 0.041 | 0.0282 |
| Time | |||
| Linear | 0.001 | 0.007 | 0.8864 |
| Interaction effect | |||
| Case × time linear | −0.017 | 0.011 | 0.1222 |
| No. of T helper lymphocytes (ln) | |||
| Case (reference, control) | −0.214 | 0.058 | 0.0002 |
| Time | |||
| Linear | −0.029 | 0.015 | 0.0532 |
| Quadratic | −0.076 | 0.026 | 0.0035 |
| Interaction effect | |||
| Case × time linear | −0.008 | 0.022 | 0.7162 |
| Case × time quadratic | 0.012 | 0.036 | 0.7389 |
| No. of cytotocix T lymphocytes (ln) | |||
| Case (reference, control) | 0.056 | 0.137 | 0.6827 |
| Time | |||
| Linear | 0.131 | 0.040 | 0.0011 |
| Interaction effect | |||
| Case × time linear | 0.077 | 0.057 | 0.1767 |
| No. of lymphocyte (ln) | |||
| Case (reference, control) | −0.123 | 0.051 | 0.0159 |
| Time | |||
| Linear | −0.039 | 0.016 | 0.0148 |
| Quadratic | −0.064 | 0.026 | 0.0138 |
| Interaction effect | |||
| Case × time linear | 0.016 | 0.022 | 0.4670 |
| Case × time quadratic | 0.024 | 0.036 | 0.5050 |
| % of natural killer cells (ln) | |||
| Case (reference, control) | 0.068 | 0.090 | 0.4499 |
| Time | |||
| Linear | 0.021 | 0.016 | 0.1894 |
| Quadratic | 0.062 | 0.027 | 0.0217 |
| Interaction effect | |||
| Case × time linear | 0.033 | 0.023 | 0.1513 |
| Case × time quadratic | 0.014 | 0.038 | 0.7126 |
| No. of natural killer cells (ln) | |||
| Case (reference, control) | −0.056 | 0.110 | 0.6107 |
| Time | |||
| Linear | −0.029 | 0.024 | 0.2269 |
| Interaction effect | |||
| Case × time linear | 0.056 | 0.034 | 0.0995 |
| % of B lymphocytes (ln) | |||
| Case (reference, control) | −0.049 | 0.077 | 0.5245 |
| Time | |||
| Linear | −0.029 | 0.012 | 0.0157 |
| Interaction effect | |||
| Case × time linear | −0.006 | 0.018 | 0.7389 |
| No. of B lymphocytes (ln) | |||
| Case (reference, control) | −0.165 | 0.090 | 0.0668 |
| Time | |||
| Linear | −0.072 | 0.019 | 0.0002 |
| Interaction effect | |||
| Case × time linear | 0.010 | 0.027 | 0.7111 |
| T helper/suppressor ratio (ln) | |||
| Case (reference, control) | −0.171 | 0.090 | 0.0574 |
| Time | |||
| Linear | 0.010 | 0.010 | 0.3173 |
| Interaction effect | |||
| Case × time linear | −0.043 | 0.015 | 0.0041 |
aAdjusted for GDS (high vs. low), education level (no schooling or primary school vs. secondary school or above), PA duration (≤180 or 181–360 vs. 361+ min), stress level (high vs. low), T_MPSS, smoking status (yes vs. no), BMI, and albumin level