Response to acute drug challenge and chronic treatment. The scores are expressed as mean TRGRS scores. Bars represent the SE. * p < 0.01 a: acute treatment. Total TRGRS scores. Improvement after l-Dopa administration was significant only in tDLB group (p < 0.001). Acute alcohol test improved tremor only in ET (p < 0.001). b Tremor in chronically treated patients clustered scores. Rest tremor is the sum of head, face, rest arms and rest leg items; postural tremor is the sum of forward arm and lateral arm items; action is the sum of kinetic, action leg, spiral and water items, mixed tremor defines any combination of rest, postural, action, standing and walking tremors