The number of 8-OHdG-positive cells. Photomicrographs showing 8-hydroxy-2'-deoxyguanosine (8-OHdG) positive cells. Immunohistochemistry in the sensory cortex at 24 h after MCAO. MCAO group (A, D); Ex + MCAO group (B, E); the number of 8-OHdG-positive cells in the sensory cortex (C, F) (Scale bar in E; 200 µm). (A, B, C) ipsilateral; (D, E, F) contralateral cortex. Graphs indicate a significant reduction in the number of 8-OHdG-positive cells in the Ex + MCAO group. Values represent the mean ± SEM. $p<0.05 vs Sham, $$p<0.01 vs Sham, ##p<0.01 vs Ex + Sham, *p<0.05 vs Ex + MCAO, **p<0.01 vs Ex + MCAO, One-way factorial ANOVA followed by Tukey’s post hoc test.