Figure 1.

The development of the prefrontal cortex is protracted in man compared to other primates. The Figure shows the synaptic density per 100 µm² in the prefrontal cortex as a function of age in man (red), chimpanzees (blue), and rhesus macaques (olive green) (error bar = 95% confidence interval). From (40) Lui et al.: Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques. Genome Research 2012; 22: 611–22. Reprinted with the kind permission of Cold Spring Harbor Laboratory Press, New York