Table 2.

Inhibition of the IFN pathway by rabies, Hendra and Nipah virus phosphoproteins products.

Virus	Family	Protein	Mechanism	References
Rabies virus	Rhabdoviridae	P	Inhibition of IRF3 phosphorylation	[89]
			by TBK1
			Sequestration of STAT1/2 in the cytoplasm	[90,91]
			Inhibition of ISGF3 binding to promoter	[92]
			Interaction with PML	[95,96]
Hendra and Nipah viruses	Paramyxoviridae	V	Inhibition of MDA-5	[98]
				[99]
		V	Lgp2 + RIG-I	[100]
		W	Inhibition of TLR3 signaling via TRIF	[101]
		P, V, W	Inhibition of STAT-1 phosphorylation	[102,103,104,105]