Table 3.

Cytotoxicity (ED₅₀ μg/mL) of compounds 5, 6, 10 and 12.

	Cell Lines					Normal Cell Line
Compounds	A549	BT483	H1299	HepG2	SAS	BEAS2B
5	15.0 ± 3.5	11.5 ± 1.8	19.2 ± 4.0	12.9 ± 3.1	10.2 ± 3.5	– a
6	16.1 ± 1.2	10.0 ± 1.8	11.8 ± 1.0	– a	17.2 ± 0.4	10.4 ± 0.3
10	6.8 ± 1.0	11.6 ± 2.8	6.7 ± 0.7	8.5 ± 1.3	9.5 ± 3.7	4.8 ± 0.7
12	12.2 ± 1.1	6.8 ± 0.6	12.8 ± 1.2	11.1 ± 0.4	10.3 ± 0.5	13.6 ± 0.5
Taxol	1.5 ± 0.9	3.9 ± 0.8	1.2 ± 0.1	1.4 ± 0.7	2.3 ± 1.5	2.3 ± 1.5

^a IC₅₀ > 20 μg/mL.