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. 2013 Mar 28;11(4):1019–1034. doi: 10.3390/md11041019

Figure 1.

Figure 1

Astaxanthin (ATX), Mithramycin A (MIT) and 1-methyl-4-phenyl-pyridine ion (MPP+) effect on cell viability of PC12 cells. (A) The effect of MPP+ on cell viability in PC12 cells. The concentrations of MPP+ were 0, 125, 250, 500, 1000, and 2000 μmol/L (compared with the vehicle control group, ** p < 0.01); (B) The effect of ATX treatment on cell viability in PC12 cells. The concentrations of ATX were 0, 1.25, 2.5, 5, 10, and 20 μmol/L (compared with the vehicle control group, * p < 0.05, ** p < 0.01); (C) The effect of MIT treatment on cell viability in PC12 cells. The concentrations of MIT were 0, 0.045, 0.09, 0.18, 0.36, and 0.72 μmol/L (compared with the vehicle control group, * p < 0.05, ** p < 0.01); (D) The effect of various treatments on cell viability. The groups were Con (control group), P (MPP+ 500 μmol/L group), M + P (MIT 0.36 μmol/L and MPP+ 500 μmol/L group), A + P (ATX 10 μmol/L and MPP+ 500 μmol/L group), M + A + P (MIT 0.36 μmol/L and ATX 10 μmol/L and MPP+ 500 μmol/L group). Viabilities were compared with the vehicle control group (* p < 0.05, ** p < 0.01) or compared with the MPP+ group (# p < 0.01).