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. 2013 Apr 8;11(4):1188–1202. doi: 10.3390/md11041188

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© 2013 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Time course of Ca_V2.2 current inhibition by application of 3 μM of RsXXIVA in rat superior cervical ganglion (SCG) neurons. (A) Symbols are mean calcium currents of the test pulse before (1), during (2) and after (3) toxin application. The test pulse was delivered every 4 s, and at the end of the experiment, 100 μM CdCl₂ was applied (4). The inset is representative of calcium currents for each condition. (B) The summary of inhibition and recovery (wash) of calcium current under toxin RsXXIVA application. * Represents p < 0.05.