Table 2. Comparison between brain temperature (°C) on admission and ischemic lesion expansion by median 5 days after stroke, change in NIHSS from admission to 5 days after stroke, and functional outcome at 3 months.
| Admission brain temperatures (°C) | DAL | PAL | PAL+ | INL | CNL |
|---|---|---|---|---|---|
| Ischemic lesion expansion by 3–5 days | |||||
| Lesion expansion | 38.8 (3) | 37.9 (7) | 38.0 (3) | 37.1 (6) | 38.3 (10) |
| No lesion expansion | 38.7 (8) | 38.0 (16) | 38.8 (13) | 37.7 (21) | 37.7 (23) |
| P value | 0.54 | 0.32 | 0.45 | 0.13 | 0.01 |
| Change in NIHSS from admission to 120 hours after stroke | |||||
| No improvement in NIHSS | 39.3 (6) | 38.8 (11) | 38.4 (9) | 38.0 (15) | 38.1 (18) |
| Improvement in NIHSS | 37.7 (4) | 37.5 (12) | 39.1 (8) | 37.3 (13) | 37.9 (15) |
| P value | 0.01 | 0.04 | 0.37 | 0.04 | 0.18 |
| Functional outcome at 3 months | |||||
| Poor outcome mRS 3-6 | 38.7 (10) | 38.6 (13) | 38.9 (8) | 37.6 (13) | 38.2 (19) |
| Good outcome mRS 0-2 | 38.8 (1) | 37.7 (11) | 38.6 (9) | 37.6 (16) | 37.6 (16) |
| P value | 0.91 | 0.31 | 0.96 | 0.59 | 0.002 |
CNL, contralateral normal brain; DAL, definitely abnormal tissue; INL, ipsilateral normal brain; PAL, possible abnormal tissue; PAL+, tissue one voxel thick immediately outside the lesion; mRS, modified Rankin Scale; NIHSS, National Institute of Health Stroke Scale.
Number in brackets is number of patients in each category. Temperatures are °C.Bold values highlight differences that are significant.