Table 1. Vital physiologic parameters of the anesthetized animals before and after treatment with Ru360 and Kaempferol.
Urethane anesthesia |
α-Chloralose anesthesia |
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MABP | pH | pCO2 | pO2 | MABP | pH | pCO2 | pO2 | |
Control | 99 ±8 (23) | 7.33± 0.1 (14) | 35± 8 (14) | 148 ±38 (14) | 101± 11 (13) | 7.34±0.09 (12) | 34 ±6 (12) | 141± 33 (12) |
Ru360-1 | 98 ±7 (12) | 7.34± 0.06 (7) | 39± 6 (7) | 153± 37 (7) | 101± 9 (7) | 7.37± 0.04 (7) | 37± 6 (7) | 153± 20 (7) |
Ru360-2 | 96± 7 (12) | 7.37 ±0.06 (7) | 38 ±7 (7) | 156± 51 (7) | 96 ±9 (7) | 7.33± 0.07 (7) | 38 ±4 (7) | 148± 20 (7) |
Kaemp-1 | 102 ±11 (11) | 7.36± 0.1 (7) | 38± 6 (7) | 139± 38 (7) | 103 ±8 (5) | 7.35 ±0.04 (5) | 34 ±5 (5) | 137± 26 (5) |
Kaemp-2 | 104± 10 (11) | 7.33 ±0.8 (7) | 37± 7 (7) | 133 ±34 (7) | 102± 10 (5) | 7.43± 0.05 (5) | 38 ±6 (5) | 134± 39 (5) |
(Number of animals are indicated in parenthesis. MABP, mean arterial blood pressure.)