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. 2013 Apr 24;33(7):1127–1137. doi: 10.1038/jcbfm.2013.64

Figure 3.

Figure 3

Oligodendrocyte morphology and organization in the central nervous system of FVB/Twitcher (Twi) mice. Immunohistochemistry using an antibody to GST-π performed on selected tissue slices from WT and Twi mice shows altered organization of the white matter in the corpus callosum (A, B), cerebellar (C–F) and spinal cord tissues (G–N) of Twi mice as compared with wild-type littermates at PND40 (A–J) and PND30 (K–N). Low-magnification pictures in A, B, C, E, G, I, K, M are montages in which 20–30 individual images (20 × ) were composed using the Photomerge tool of Adobe Photoshop CS4. Higher magnification images (40 × ) in D, F, H, J, L, N show altered morphology and cell organization of GST-π+ cells in the cerebellum and spinal cord of Twi mice. Scale bars: 500 μm (A, B), 250 μm (C, E, G, I, K, M), 100 μm (D, F, H, J, L, N).