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. Author manuscript; available in PMC: 2013 Jul 9.
Published in final edited form as: Biopharm Drug Dispos. 2012 Dec 3;34(2):98–106. doi: 10.1002/bdd.1826

Figure 1.

Figure 1

(A) Effect of phenethyl isothiocyanate (PEITC) on tumor-free survival in NMU-treated rats. N-methyl nitrosourea was administered at a dose of 50 mg/kg i.p. at day 0 and between 12 and 15 days. Rats were administered 150 µmol/kg or 50 µmol/kg PEITC in corn oil every 2 days or corn oil alone in the vehicle-treated control group. The black line represents the control group (n = 30), the green dashed line represents the 50 µmol/kg PEITC-treated group (n=20) and the red dotted line represents the 150 µmol/kg PEITC-treated group (n = 29). Curves were determined to be significantly different between the control and treatment groups (Log rank test, p < 0.05). (B) Effect of PEITC on tumor incidence and (C) average number of tumors per group. In panels B and C, the open bar represents the controls, while the gray bar represents the 50 µmol/kg PEITC-treated group, and the black bar represents the 150 µmol/kg PEITC-treated group. *Statistically significant differences from the control group (p < 0.05)