Table 2.
The median histopathologic scores of wound healing were determined in the extract-treated and control groups by using a modified 0 to 4 numerical scale. The scores were 0 for absence, 1 for occasional presence, 2 for light scattering, 3 for abundance, and 4 for confluence of cells or fibres.
| Groups | Epithelialisation | Inflammatory cell infiltration | Fibroblast proliferation | Neovascularisation | Collagen deposition |
|---|---|---|---|---|---|
| G1 (high dose) | 3.83 ± 0.41a | 1.50 ± 0.55b | 3.50 ± 0.55a | 2.67 ± 0.52a | 3.83 ± 0.41a |
| G2 (low dose) | 3.17 ± 0.41a | 1.83 ± 0.75b | 3.17 ± 0.75a | 2.00 ± 0.63a | 3.33 ± 0.52a |
| G3 (Intrasite gel) | 3.50 ± 0.55a | 1.67 ± 0.52b | 3.33 ± 0.82a | 2.17 ± 0.75a | 3.67 ± 0.52a |
| G4 (CMC, control) | 0.83 ± 0.41b | 3.67 ± 0.52a | 1.00 ± 0.00b | 0.83 ± 0.75b | 1.17 ± 0.41b |
Data are expressed as mean ± standard error (n = 6). Different letters (a and b) in a column indicate significant difference (P < 0.05).